Plants of the American continent with antimalarial activity

Revista Brasileira de Farmacognosia

Diniz, Margareth de Fátima F. M.¹  Cunha, Emídio Vasconcelos L. da¹  Sousa, Layanna C. F. de¹  Silva, Marcelo S.¹  Barbosa-Filho, José M.¹  Mariath, Ingrid R.¹  Batista, Leônia M.¹  Falcão, Heloina de S.¹  Athayde-Filho, Petrônio F.¹  Tomaz, Anna Cláudia de A.¹  Tavares, Josean Fechine¹  Universidade Federal da Paraíba, João Pessoa, Brazil¹ 

关键词: Antimalarial activity;    medicinal plants;    natural products;    American continent;    review.;   

DOI  :  10.1590/S0102-695X2009000100026

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

Malaria is a human parasitic disease caused by protozoa species of the Plasmodium genus. This disease has affected populations of the tropical and subtropical regions. About 500 million new cases occur annually on the world and therefore it is considered an emerging disease of important public health problem. In this context, the natural products as vegetables species have their bioactive molecules as targets for pharmacological, toxicological and phytochemical studies towards the development of more effective medicines for the treatment of many diseases. So this work intends to aid the researchers in the study of natural products to the treatment of malaria. In this review, 476 plants of the American continent were related for the antimalarial activity and of these vegetables species 198 were active and 278 inactive for some type of Plasmodium when they were evaluated through of in vitro or in vivo bioassays models.

【 授权许可】

Unknown