Chemical and anti-ulcer evaluation of Jodina rhombifolia (Hook. & Arn.) Reissek extracts

Revista Brasileira de Farmacognosia

Schenkel, Eloir P.¹  Dresch, Ana P.¹  Montanha, Jarbas A.¹  Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil¹  Langeloh, Augusto¹  Universidad Autónoma del Estado de Morelos, Morelos, México¹  Universidade Federal de Santa Catarina, Florianópolis, Brazil¹  Cardoso-Taketa, Alexandre T.¹  Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil¹  Dallegrave, Eliane¹ 

关键词: Jodina rhombifolia;    Santalaceae;    anti-ulcer;    C-glycosylflavonoids;    vicenin-2.;   

DOI  :  10.1590/S0102-695X2009000100007

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) is a medicinal plant popularly used as an anti-ulcer medicine. The plant native from Southern Brazil was chemically investigated and tested for its in vivo gastric anti-ulcer property by chloride acid/ethanol model. The chromatographic analysis of the hydroethanol extract of its leaves revealed the presence of C-glycosylflavonoids. From the n-butanol fraction of the hydroethanol extract of its aerial parts, vicenin-2 was isolated as the main component and identified by spectroscopic methods; and, a direct comparison with authentic samples was made. This fraction afforded three other C-glycosylflavonoids: vitexin, orientin and swertisin; all of them identified by direct comparison with authentic samples. We found that the oral administration of aqueous and hydroethanolic extracts led to a significant decrease in the ulcer index.

【 授权许可】

Unknown