In vitro assessment of antibacterial activity of a dental cement constituted of a Copaifera multijuga Hayne oil-resin

Revista Brasileira de Farmacognosia

Universidade Federal do Amazonas, Manaus, Brasil¹  Veiga Junior, Valdir Florêncio da¹  Centro de Biotecnologia da Amazônia, Manaus, Brasil¹  Vasconcelos, Kátia Regina Felizardo¹  Rocha, Waldireny Caldas¹  Bandeira, Maria Fulgência Costa Lima¹ 

关键词: Copaiba oil;    antibacterial activity;    dental cements;    Copaifera multijuga;    Fabaceae.;   

DOI  :  10.1590/S0102-695X2008000500017

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

One of the materials utilized for suitability of the oral means in the public service is the cement produced from zinc oxide and eugenol. However, eugenol is a cytotoxic substance that can trigger some adverse effects. For this reason, it is desired to replace eugenol for another substance that presents low toxicity, keeping or even improving the cement properties. The copaiba oil-resin is a natural product, utilized by the Amazonian population and recognized for its medicinal properties. Based on the properties of this oil-resin, on the proven antimicrobial activity of calcium hydroxide and on the anti-septic action of zinc oxide, it was proposed to formulate a dental cement obtained through the association of ZnO, Ca(OH)2 and Copaifera multijuga Hayne oil-resin and assess its antibacterial activity through the test of dilution in aqueous medium against the standard of Streptococcus mutans (ATCC 25175) and S. sanguinis (ATCC 15300). In this assay, the following experimental groups were utilized: the cement containing ZnO, Ca(OH)2 and copaiba oil-resin (G1) and each one of the constituents individually, ZnO (G2), Ca(OH)2 (G3) and copaiba oil-resin (G4). All the analyzed groups showed antibacterial activity, G4 showed the best results and G1 showed itself to be a promising cement for application in dentristy.

【 授权许可】

Unknown