In vitro evaluation of the antioxidant, anti-inflammatory and antimicrobial activities of the montanine alkaloid

Revista Brasileira de Farmacognosia

Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil¹  Zuanazzi, José Ângelo S.¹  Menezes, Fábio S.¹  Henriques, Amélia T.¹  Castilhos, Tatiana S.¹  Giordani, Raquel B.¹  Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil¹ 

关键词: Amaryllidaceae;    Rhodophiala bifida;    montanine;    alkaloids.;   

DOI  :  10.1590/S0102-695X2007000200013

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

Several biological properties, such as antiparasite, antitumor, antiviral and anticholinesterasic activities, are associated with extracts and isolated products, including alkaloids from Amaryllidaceae species. In this study, the antioxidant activity and inhibitory action on the growth of cell cultures of Saccharomyces cerevisae (ATCC 2601), Pseudomonas aeruginosa (ATCC 27853), Staphylococcus aureus (ATCC 6538), Staphylococcus epidermides (ATCC 12228) and Escherichia coli (ATCC 25922) were observed to the montanine alkaloid, isolated from the bulbs of Rhodophiala bifida (Herb.) Traub (Amaryllidaceae). The anti-inflammatory activity, which was evaluated through the sample antichemotaxis ability determination, was not significant in the used dose.

【 授权许可】

Unknown