期刊论文详细信息
Revista Brasileira de Farmacognosia | |
Pharmacological effects of the monoterpene alpha,beta-epoxy-carvone in mice | |
Universidade Federal de Sergipe, São Cristóvão, Brazil1  Leite, José R.1  Mattei, Rita1  Universidade Federal de São Paulo, São Paulo, Brazil1  Nóbrega, Franklin F. F.1  Almeida, Reinaldo N. de1  Sousa, Damião P. de1  Claudino, Fladmir S.1  Universidade Federal da Paraíba, João Pessoa, Brazil1  | |
关键词: Pharmacological effects; essential oil; monoterpene; a; b-epoxy-carvone; mice.; | |
DOI : 10.1590/S0102-695X2007000200006 | |
来源: Sociedade Brasileira de Farmacognosia | |
【 摘 要 】
The monoterpene a,b-epoxy-carvone (EC) in doses of 200, 300 or 400 mg/kg injected by i.p. route in mice caused a significant decrease in the motor activity of animals when compared with the control group, up to 120 minutes after the administration. The doses of 300 or 400 mg/kg had induced a significant increase of in the sleeping time of animals not having modified, however, the latency. The EC in the dose of 400 mg/kg reduced the remaining time of the animals on the rotating rod (Rotarod test). These results suggest a possible central effect.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912010144962ZK.pdf | 204KB | download |