Coumarinic artifacts isolated from Polygala paniculata L. (Polygalaceae)

Revista Brasileira de Farmacognosia

Branco, A.¹  Cristiano, R.¹  Monache, F. D.¹  Pizzolatti, M. G¹  Universidade Federal de Santa Catarina, Florianópolis¹  Universitá Cattolica Del Sacro Cuore, Roma, Itália¹ 

关键词: Polygala paniculata;    Polygalaceae;    coumarin;    artifacts;    NMR.;   

DOI  :  10.1590/S0102-695X2002000100003

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

Fractionation of a chloroform extract of Polygala paniculata (Polygalaceae) on silica gel column chromatography yielded 7-methoxy-8-(1',2'-epoxy-3'-methyl-3'-butenyl)-coumarin (1) and two coumarinic artifacts (2a-2b). The reaction of 1 with EtOH/SiO2 at room temperature for 24 hours yielded 7-methoxy-8-(1'-hydroxy-2'-ethoxy-3'-methyl-3'-butenyl)-coumarin (2a) and 7-methoxy-8-(1'-ethoxy-2'-hydroxy-3'-methyl-3'-butenyl)-coumarin (2b). The structures have been determined by spectral data, including 2D NMR experiments.

【 授权许可】

Unknown