Chemistry and Toxicology of Sulphur Mustard- A Review

Defence Science Journal

R. C. Malhotra¹  K. Ganesan¹  R. V. Swamy¹  K. Sugendran¹ 

[1] Defence Research & Development Establishment, Gwalior

关键词: Chemical warfare agent;    Sulphur mustard;    Bis2 chloroethyl sulphide;   

DOI  :  

学科分类：社会科学、人文和艺术（综合）

来源: Defence Scientific Information & Documentation Centre

【 摘 要 】

Bis (2-chloroethyl) sulphide commonly known as sulphur mustard (SM) is highly reactive bifunctional compound, documented as antimitotic, mutagenic, carcinogenic, teratogenic and cytotoxic agent. It is a powerful vesicant and has been employed as a chemical warfare agent. Skin, eyes and respiratory tract are the principal target organs and the deoxyribose nucleic acid (DNA) is the most important molecular target of SM toxicity. There is no specific antidote for SM injury .Treatment to SM toxicity is symptomatic.

【 授权许可】

Unknown