Suppression of Lymphocyte Blastogenesis in Cows with Puerperal Metritis and Mastitis

Journal of Veterinary Medical Science

Toshiyuki SUZUKI¹  Shigeru SATO¹  Keiji OKADA¹ 

关键词: lymphocyte blastogenesis;    mastitis;    puerperal metritis;   

DOI  :  10.1292/jvms.57.373

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(18)Cited-By(6)Mitogenic responses of peripheral blood lymphocytes in naturally occurring clinical puerperal metritis and mastitis were investigated. Glucose consumption index (GCI) values for phytohaemagglutinin (PHA), concanavalin A (Con A) and pokeweed mitogen (PWM) in the puerperal metritic cows and mastitic cows were significantly lower than those in the healthy cows. Suppression of lymphocyte blastogenesis was correlated to an increased concentration of serum ammonia in the puerperal metritic cows, and of α1-acid glycoprotein (α1AG) in the mastitic cows. Lymphocyte blastogenesis in the mastitic cows was also correlated to the serum concentration of vitamin E. These findings indicate that the puerperal metritic and mastitic cows are associated with impaired lymphocyte blastogenesis.

【 授权许可】

Unknown