Effects of Fighting after Grouping on Plasma Cortisol Concentration and Lymphocyte Blastogenesis of Peripheral Blood Mononuclear Cells Induced by Mitogens in Piglets

Journal of Veterinary Medical Science

Masao AKUZAWA¹  Eisaburo DEGUCHI¹ 

[1] Department of Veterinary Internal Medicine, Faculty of Agriculture, Kagoshima University

关键词: fighting;    grouping;    lymphocyte blastogenesis;    piglet;    plasma cortisol;   

DOI  :  10.1292/jvms.60.149

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(19)Cited-By(17)One litter (Group A) of three unacquainted groups of littermates (4 piglets/litter), 64.0 ± 0.8 days old, was moved to the pen of another litter (Group B) and they were housed together for 19 days after grouping (phase 1). The pigs in Group B violently attacked all the pigs in Group A for 9 hr after grouping. The remaining group was not grouped and used as controls. The plasma cortisol concentrations 1 hr after grouping were significantly higher than those 1 hr before and 24 hr after grouping, and the suppression of lymphocyte blastogenesis of peripheral blood mononuclear cells (PBMC) induced by mitogens was observed on 3, 8 and 19 days after grouping. After phase 1 ended, the pigs in Group A were returned to their own pen for 7 days, and then they were regrouped with the pigs in Group B and reared together for a further 14 days. Neither agonistic behavior nor change of plasma cortisol after regrouping was seen. Though the lymphocyte blastogenesis of PBMC induced by the mitogens on day 0 after regrouping was significantly lower in the pigs of Groups A and B compared to those in control pigs, a significant difference in lymphocyte blastogenesis among three groups was not seen on 7 and 14 days after regrouping. These findings indicate that fighting after grouping unacquainted litters increases plasma cortisol, and suppresses lymphocyte blastogenesis for 26 days after grouping.

【 授权许可】

Unknown