Infectious hematopoietic necrosis virus antibody profiles in naturally and experimentally infected Atlantic salmon Salmo salar

Diseases of Aquatic Organisms

Scott E. LaPatra¹  Sophie St-Hilaire¹  Michael L. Kent¹  Stacy Chartrand¹  Carl S. Ribble¹ 

关键词: IHNV;    IHNV-specific antibodies;    Surveillance;    Convalescent carrier state;    Atlantic salmon;   

DOI  :  10.3354/dao046007

学科分类：生物科学（综合）

来源: Inter-Research

【 摘 要 】

ABSTRACT: Atlantic salmon Salmo salar naturally and experimentally exposed to infectious hematopoietic necrosis virus (IHNV) in British Columbia, Canada, developed antibodies against the virus. More than 50% of the fish exposed to IHNV remainedseropositive for several months after the IHN epizootic had subsided. The virus itself could not be detected in asymptomatic fish once the fish had recovered from IHN. The persistence of IHNV-specific antibodies in a large percentage of Atlantic salmon,from 4 different populations that survived an outbreak of IHN, and the lack of IHNV-specific antibodies in fish with no history of the disease, suggests that serology may be a useful tool for determining previous exposure to the virus. It may be importantto determine whether Atlantic salmon have been infected with IHNV because, although the virus is difficult to detect in asymptomatic fish, an incidental finding suggests it may persist in a small number of fish after the outbreak has subsided.Furthermore, the presence of seropositive fish would be an indication that the virus may be enzootic at a farm, and such information would thus aid producers with stocking decisions.

【 授权许可】

Unknown