Glyco-metabolic profile among type 2 diabetic patients with erectile dysfunction

Endocrine Journal

Pamela Maffioli²  Aldo Bonaventura²  Gianluca Ferrara²  Giuseppe Derosa²  Angela D’Angelo²  Lucio Bianchi²  Davide Romano²  Carmine Tinelli¹  Elena Fogari² 

[1] Biometric Unit, Fondazione IRCCS Policlinico S. Matteo, Pavia 27100, Italy;Department of Internal Medicine and Therapeutics, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia 27100, Italy

关键词: Erectile dysfunction;    Type 2 diabetes mellitus;    Hyperinsulinemia;    Testosterone;    International Index of Erectile Function (IIEF);   

DOI  :  10.1507/endocrj.EJ12-0117

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(41)Cited-By(3)The aim of this study was to evaluate the glyco-metabolic profile among type 2 diabetic patients with erectile dysfunction (ED).We evaluated 88 type 2 diabetic males, aged 62.78±9.26 years.We administered patients the IIEF (International Index of Erectile Function) questionnaire to assess erectile function, organ function, sexual desire, and satisfaction level during and after the sexual intercourse and the SAS (self-rating anxiety scale) and SDS (self-rating depression scale) questionnaires to evaluate anxiety and depression.We evaluated: BMI, abdominal circumference, glycated hemoglobin (HbA1c), fasting plasma glucose (FPG), fasting plasma insulin (FPI), HOMA index, lipid profile, testosterone, free testosterone, dihydrotestosterone, and sex hormone binding globulin (SHBG).The IIEF questionnaire showed that in the examined sample there were 50 patients (56.8%) affected by ED, and 38 patients (43.2%) without ED.Comparing the two groups, 57.9% of patients without ED, and 70.0% of patients with ED were smokers, and the difference between the two groups was significant (pp1c.Furthermore, patients with ED had higher levels of FPI, and lower levels of testosterone and dihydrotestosterone.The prevalence of ED in Italian type 2 diabetic males with mean age of 62 years is about 56% and it is linked to higher levels of FPI, but lower levels of HbA1c, free testosterone and dihydrotestosterone.

【 授权许可】

Unknown