Journal of Veterinary Medical Science | |
The Prokinetic Effect of Mosapride Citrate on Horse Gastric Emptying Rates | |
Morito FUKUNAKA2  Naoki SASAKI2  Haruo YAMADA2  Hisashi INOKUMA2  Koichi OKAMURA1  | |
[1] The United Graduate School of Veterinary Sciences, Gifu University;Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine | |
关键词: equine; gastric emptying rate; mosapride citrate; | |
DOI : 10.1292/jvms.70.627 | |
学科分类:兽医学 | |
来源: Japanese Society of Veterinary Science | |
【 摘 要 】
References(15)Cited-By(4)The prokinetic effect of the 5-HT4 receptor agonist mosapride was evaluated in seven healthy thoroughbreds. Mosapride was orally administerd at doses of 0.5, 1.0 or 1.5 mg/kg. The breath 13CO2/12CO2 rate (Δ13CO2), an indirect indicator for the rate of gastric empting, was measured at appropriate points for 4 hr after drug administration. There was a significant increase compared with the control value at 15, 20 and 165 min for 0.5 mg/kg, 30 min at 1.0 mg/kg and 165 min for 1.5 mg/kg. The results suggest that mosapride may facilitate the gastric emptying in horses.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201911300889509ZK.pdf | 135KB | download |