Efficacy of Fosfomycin on Escherichia coli Isolated from Bitches with Pyometra

Journal of Veterinary Medical Science

Sanae SHIBATA²  Ikuo INOUE¹  Tsuneo FUKATA¹ 

[1] The United Graduate School of Veterinary Sciences, Gifu University, 1–1 Yanagido, Gifu 501–1193, Japan;Department of Veterinary Sciences, Faculty of Applied Biological Sciences Gifu University, 1–1 Yanagido, Gifu 501–1193, Japan

关键词: antimicrobial resistance;    bitch;    Escherichia coli;    fosfomycin;    pyometra;   

DOI  :  10.1292/jvms.12-0489

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(20)Cited-By(1)The aim of this study was to determine the antimicrobial resistance of Escherichia coli isolated from the uteri of bitches with pyometra, and 38 E. coli isolates were used. The antimicrobials used were ampicillin (ABPC), amoxicillin/clavulanic acid, gentamicin, minocycline, cefazolin, levofloxacin (LVFX), trimethoprim-sulfamethoxazole (ST) and fosfomycin (FOM). Resistance to ABPC occurred most frequently, followed by LVFX and ST. Multi-drug resistance, defined as resistance against 3 or more classes of antimicrobials, was found in 23.7% of all isolates. Nine out of 13 resistant strains were multi-drug resistant, but no strain was found to be resistant to FOM. This suggests that FOM should be administered for E. coli from pyometra.

【 授权许可】

Unknown