Journal of Veterinary Medical Science | |
Hemodynamic Alterations in Dogs with Shock Induced by Intravenous Injection of Heartworm Extract | |
Chikao MIKAMI1  Hitoshi KITAGAWA1  Katsuya KITOH1  Yoshihide SASAKI1  | |
[1] Laboratory of Internal Medicine, Division of Veterinary Medicine | |
关键词: heartworm; hemodynamics; shock; | |
DOI : 10.1292/jvms.63.179 | |
学科分类:兽医学 | |
来源: Japanese Society of Veterinary Science | |
【 摘 要 】
References(21)Cited-By(1)To elucidate one way of the shock mechanisms, the hemodynamic alterations were examined in 7 dogs with heartworm (HW) extract-induced shock. The first alteration observed after injection of HW extract was a decrease in right ventricular end-diastolic pressure (RVEDP). After that, left ventricular (LV) end-diastolic pressure, LV systolic pressure, and LV dp/dt fell significantly, followed by a decrease in the cardiac output of all dogs to below the detectable level (1.00 l/min). Since RVEDP depends on blood flow into the right ventricle, the decrease in RVEDP means a reduction in venous return. Therefore, this study showed that the first trigger of a decrease in blood pressure in HW extract-induced shock is the reduction in venous return.
【 授权许可】
Unknown
【 预 览 】
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RO201911300844489ZK.pdf | 147KB | download |