The aetiology of anaemia during pregnancy: a study to evaluate the contribution of iron deficiency and common infections in pregnant Ugandan women

Public Health Nutrition

Dorine W Swinkels¹  Lena Davidsson¹  Harold Tjalsma¹  Rhona K Baingana¹  John K Enyaru¹ 

关键词: Anaemia;    Iron status;    Pregnancy;    Infection;    Uganda;   

DOI  :  10.1017/S1368980014001888

学科分类：卫生学

来源: Cambridge University Press

【 摘 要 】

AbstractObjectiveTo describe the aetiology of anaemia in pregnant Ugandan women and explore Fe deficiency and common infections as contributors to anaemia in this population.DesignCross-sectional study in which Hb, ferritin, transferrin receptor (sTfR), C-reactive protein, α-1 acid glycoprotein, hepcidin, malaria, hookworm infestation, syphilis and Helicobacter pylori infection were assessed.SettingAntenatal care clinic at Kawempe Health Centre, Kampala, Uganda.SubjectsHIV-negative women (n 151) in their first or second pregnancy at 10–16 weeks’ gestation.ResultsThe prevalence of anaemia was 29·1 %. Fe deficiency was 40·4 % and 14·6 % based on ferritin 8·3 μg/ml and presence of malaria parasites were 41·6 (95 % CI 11·1, 72·2) %, 13·5 (95 % CI 2·0, 25·0) % and 12·0 (95 % CI 1·4, 22·6) %, respectively.ConclusionsInfections and inflammation are of greater significance than Fe deficiency in the aetiology of anaemia in pregnant Ugandan women during the first trimester.

【 授权许可】

Unknown