The association between serum lipids and colorectal neoplasm: a systemic review and meta-analysis

Public Health Nutrition

Keming Wang¹  Yun Tian¹  Zhaoxia Wang¹  Yingrui Fan¹  Ying Ye¹  Juan Li¹  Yi Li¹  Jirong Wang¹  Guozhong Ji¹ 

关键词: Serum lipids;    Colorectal adenoma;    Colorectal cancer;    TAG;    Meta-analysis;   

DOI  :  10.1017/S1368980015000646

学科分类：卫生学

来源: Cambridge University Press

【 摘 要 】

AbstractObjectiveThere have been inconsistent results published regarding the relationship between dyslipidaemia and an increased risk of colorectal neoplasia (CRN), including colorectal adenoma (CRA) and colorectal cancer (CRC). We conducted a meta-analysis to explore the relationship between dyslipidaemia and CRN.DesignWe identified studies by performing a literature search using PubMed, EMBASE and the Science Citation Index through October 2013.SettingWe analysed thirty-three independent studies reporting the association between CRN and at least one of the selected lipid components, including total cholesterol (TC), TAG, HDL-cholesterol (HDL-C) and LDL-cholesterol (LDL-C).SubjectsCRN cases (n 21 809) were identified.ResultsOverall, people with high levels of serum TAG (risk ratio (RR)=1·08; 95 % CI 1·05, 1·12, P

【 授权许可】

Unknown