Nucleotide Sequences of Glycoprotein I and E Genes of Equine Herpesvirus Type 4

Journal of Veterinary Medical Science

Chieko KAI²  Takeshi MIKAMI²  Ken MAEDA¹  Tomio MATSUMURA³  Naoaki YOKOYAMA²  Takayuki MIYAZAWA²  Armando Mario DAMIANI² 

[1] Department of Veterinary Microbiology, Faculty of Agriculture, Yamaguchi University;Department of Veterinary Microbiology, Faculty of Agriculture, The University of Tokyo;Epizootic Research Station, Equine Research Institute, The Japan Racing Association

关键词: equine herpesvirus type 4;    glycoprotein E;    glycoprotein I;   

DOI  :  10.1292/jvms.60.219

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(42)Cited-By(1)The nucleotide sequences of the glycoprotein I (gI) and E (gE) genes of equine herpesvirus type 4 (EHV-4) strain TH20 were determined. The predicted region encoding the EHV-4 gI gene is 1,263 nucleotides, corresponding to a polypeptide of 420 amino acids in length. The predicted region encoding the EHV-4 gE gene is 1,647 nucleotides, corresponding to a polypeptide of 548 amino acids in length. The EHV-4 gI and gE genes show 74% and 85% identity at the amino acid level with those of equine herpesvirus type 1 (EHV-1), respectively. Furthermore, we have found an open reading frame homologous to the EHV-1 gene 75, which overlaps in part with the 3' end of EHV-4 gE gene. These sequence data will be useful for development of a modified live vaccine against equine herpesvirus type 1 and 4 infections.

【 授权许可】

Unknown