Epidermal Growth Factor Receptor Protein Expression and Gene Amplification in Normal, Hyperplastic, and Cancerous Glottic Tissue: Immunohistochemical and Fluorescent in Situ Hybridization Study on Tissue Microarrays

Croatian Medical Journal

Hadžisejdić, Ita¹  Jonjić, Nives¹  Manestar, Dubravko²  Krstulja, Mira¹  Manestar, Darko²  Kujundžić, Milodar²  Braut, Tamara²  Grahovac, Blaženka¹ 

[1] Department of Pathology, School of Medicine, University of Rijeka, Croatia;Department of Otorhinolaryngology Head and Neck Surgery, Clinical Hospital Center Rijeka, Croatia

关键词: EGFR;    quantitative immunohistochemistry;    FISH;    glottic cancer;    tissue microarray;    EGFR-targeted therapies;   

DOI  :  

学科分类：卫生学

来源: Medicinska Naklada Co.

【 摘 要 】

Aim To evaluate the importance of epidermal growth factor receptor (EGFR) protein overexpression and gene amplification in carcinogenesis of glottic cancer. Method In order to evaluate EGFR expression at protein and gene level,...

【 授权许可】

Unknown