HPV infection, risk factors and viral load among Mexican male college students

Brazilian Journal of Infectious Diseases

Vera-Uehara, Carmina²  Olamendi-Portugal, Ma. Leónidez²  Conde-Glez, Carlos Jesús²  Sánchez-Alemán, Miguel Angel²  Ramos-Castañeda, José²  Uribe-Salas, Felipe Javier¹ 

[1]Colegio de la Frontera Norte, Piedras Negras, Mexico

[2]Instituto Nacional de Salud Pública, Cuernavaca, Mexico

关键词: HPV;    Viral load;    Contraceptive pills;    Risky sexual behaviors;    Male;    Students;   

DOI  :  10.1016/j.bjid.2013.05.006

来源: Contexto

【 摘 要 】

Objectives:To determine the prevalence of HPV and the risky sexual behaviors associated to it in a sample of male college students, taking into account genotype and viral load.Methods:From 2002 to 2003, male students from the Autonomous University of Morelos State completed a questionnaire and provided self-collected genital samples to detect and quantify HPV. We performed a bivariate and a multivariate logistic regression analysis to identify correlates associated with the infection and to assess the viral load as a function of the viral infecting type. The fragments of β-globin gene and L1 of HPV, were amplified, purified and cloned, to evaluate viral load.Results:Among 253 subjects, HPV prevalence was 19.4%, and HPV16 was the most common subtype. History of STIs (OR = 4.8; 95% CI 1.2–18.9), contraceptive pill use by female partner (OR = 2.6; 95% CI 1.1–6.3) and exchanging sex for money (OR = 4.9; 95% CI 1.2–20) were associated to the HPV infection. HPV16 viral load was 7.8 copies (HPV/beta-globin) compared to 0.9 copies for other HPV types.Discussion:HPV16 displayed the highest viral load, and it was the most prevalent. It was found that using contraceptive pills by female partners was associated with HPV infection.

【 授权许可】

Unknown