Genetically Hypertensive Brown Norway Congenic Rat Strains Suggest Intermediate Traits Underlying Genetic Hypertension

Croatian Medical Journal

Bilušić, Marijo⁸  Grigor, Murray R.¹  Jacob, Howard J.⁷  Kwitek, Anne E.²  Weder, Alan⁴  Hunt, Steven C.^1,9  Harris, Eugenie L.³  Curb, J. David^1,10  Moreno, Carol¹¹  Boerwinkle, Eric⁵  Barreto, Nadia E.⁷  Thompson, Caryn M.⁶  Tschannen, Michael R.¹¹  Porteous, William K.³ 

[1]Department of Biochemistry, University of Otago, New Zealand

[2]Department of Internal Medicine, University of Iowa, Iowa City, USA

[3]Childrens Hospital of Wisconsin, Milwaukee, Wis, USA

[4]University of Michigan Hospital, Ann Arbor, Mich, USA

[5]Human Genetics Center, University of Texas, Houston, Tex, USA

[6]Department of Bioinformatics and Biostatistics, University of Louisville, Ky, USA

[7]Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wis, USA

[8]Trinitas Hospital, Department of Internal Medicine, Seton Hall University, Elizabeth, NJ, USA

[9]University of Utah, Salt Lake City, Utah, USA

[10]The Honolulu Hearth Program Pacific Health Research Institute, Honolulu, Hawaii, USA

[11]Department of Physiology, Medical College of Wisconsin, Milwaukee, Wis, USA

关键词: Genetically Hypertensive rat;    congenic;    angiotensin II;    baroreceptor reflex;    QTL;    hypertension;   

DOI  :  

学科分类：卫生学

来源: Medicinska Naklada Co.

【 摘 要 】

Aim To determine the independent and combined effects of three quantitative trait loci (QTL) for blood pressure in the Genetically Hypertensive (GH/Omr) rat by generating and characterizing single and combined congenic strains that have...

【 授权许可】

Unknown