Intracranial Granular Cell Tumor in a Dog

Journal of Veterinary Medical Science

Yung-Chang LIN¹  Chiung-Hsiang CHENG⁵  Sao-Ling LIANG³  Chen-I LIU⁵  Chin-Cheng LEE⁴  Sun-Chau HUANG²  Chen-Hsuan LIU⁵  Wei-Chih HSU⁴ 

[1]Department of Veterinary Medicine, College of Veterinary Medicine, National Chung-Ching University

[2]Graduate Institute of Electrical Engineering, National Taiwan University

[3]Veterinary Hospital, National Taiwan University

[4]Department of Pathology and Laboratory Medicine , Shin Kong Wu-Ho-Su Memorial Hospital

[5]Department of Veterinary Medicine, National Taiwan University

关键词: canine;    granular cell tumor;    intracranial;   

DOI  :  10.1292/jvms.66.77

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(20)Cited-By(3)A 12-year-old female miniature poodle showed a 3-month history of neurological signs. Magnetic resonance imaging disclosed a high intensity tumor mass in the right cerebral hemisphere with compression of the lateral ventricle. At necropsy, a 2 × 3 cm white, friable mass was found in the right ventral pyriform lobe. Microscopically, the tumor cells were large, polygonal to round cells supported by a sparse fibrovascular stroma. The tumor cells typically possesed finely granular, pale eosinophilic cytoplasm with strongly positive periodic acid-Schiff (PAS) reaction. The tumor cells were immunopositive for vimentin, NSE and S-100. Ultrastructurally, the tumor cells showed large amounts of granules in the cytoplasm, and absence of basement membrane. Based on the above-mentioned findings, the intracranial granular cell tumor was diagnosed.

【 授权许可】

Unknown