Dependency rather than old age increases the risk of warfarin-related bleeding

British Journal of General Practice

Geraldine Fairfield¹  Peter T Donnan¹  Philip G Cachia¹  Barclay M Goudie¹  Sally S Al-Agilly¹ 

[1] West Gate Health Centre, Dundee

关键词: aged;    anticoagulants;    dependency;    haemorrhage;    risk;    warfarin;   

DOI  :  

学科分类：卫生学

来源: Royal College of General Practitioners

【 摘 要 】

There is uncertainty about the safety of anticoagulation with warfarin in the elderly. This cohort study investigated the risk factors for warfarin-related bleeding in a primary care setting. In multiple regression analyses increased risk of bleeding was associated with domiciliary monitoring of international normalised ratio (INR), low proportion of INR tests in the target range, high intensity of anticoagulation, and male sex. Age was not associated with increased risk after adjustment. High levels of dependency, not old age, should raise concerns about the safety of anticoagulation with warfarin.

【 授权许可】

Unknown