Intestinal Spirochetosis in a 21-Month-Old Thoroughbred Colt

Journal of Veterinary Medical Science

Yasushi KUWAMOTO¹  Atsutoshi KUWANO³  Yoshiharu ISHIKAWA²  Koichi KADOTA²  Tomoyuki SHIBAHARA²  Takanori UENO³  Taiji MAEDA²  Toru ANZAI¹  Hiroaki SATO⁴ 

[1] Epizootic Research Station, Equine Research Institute;Hokkaido Research Station, National Institute of Animal Health;Clinical Science and Pathobiology Division, Equine Research Institute, Japan Racing Association (JRA);Hidaka Yearling Training Farm of Japan Racing Association

关键词: Brachyspira;    equine;    intestinal spirochete;   

DOI  :  10.1292/jvms.64.633

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(11)Cited-By(1)A 21-month-old Thoroughbred colt showed continuous diarrhea and developmental retardation for 7 months, and was thereafter subjected to euthanasia for necropsy and laboratory examinations. At necropsy, the cecal and colonic mucosae were diffusely rough and hyperemic. Histopathologically, the mucosa and submucosa were edematous and were infiltrated by numerous lymphocytes and macrophages. Meanwhile, three morphological types of Brachyspira antigen-containing spirochetes were found to be numerous in the crypts and in the mucus layer over the epithelium in the cecal and colonic lesions. They were frequently observed in intercellular gaps and in the cytoplasm of degenerative epithelial cells, and in the lamina propria, particularly in cavities around blood vessels. These invasive intestinal spirochetes might be one of pathogens inducing colitis and diarrhea in horses.

【 授权许可】

Unknown