Toxicity against Artemia salina of the zoanthid Palythoa caribaeorum (Cnidaria: Anthozoa) used in folk medicine on the coast of Pernambuco, Brazil

Biotemas

Lourinalda Luiza Dantas da S. S. de Oliveira¹  Claudio Augusto Gomes da Camara¹  Jeanne Claine de Albuquerque Modesto²  Liany Figuerêdo de Andrade Melo³  Carlos Daniel Pérez³ 

[1] Universidade Federal Rural de Pernambuco;Universidade Federal de Perambuco;Universidade Federal de Pernambuco

关键词: Artemia salina;    Organic extracts;    Pernambuco;    Toxicity;    Zoanthidea;   

DOI  :  

学科分类：生物科学（综合）

来源: Universidade Federal de Santa Catarina * Centro de Ciencias Biologicas

【 摘 要 】

http://dx.doi.org/10.5007/2175-7925.2012v25n3p145  Palythoa caribaeorumis a zoanthid whose mucus is traditionally used by fishermen communities on the southern coast of the state of Pernambuco as an anesthetic and anti-inflammatory agent, as well as for the treatment of topical wounds. In order to evaluate a possible toxicity, hexane and ethanol extracts of the zoanthid obtained from the beaches of Piedade (PCP-H; PCP-E), Guadalupe (PCG-H; PCG-E), and Suape (PCS-H; PCS-E) were tested againstArtemia salinalarvae. Among the six extracts tested, PCP-H, PCP-E, PCS-H, and PCS-E showed low toxicity, with LC50 values above 250µg/mL. On the other hand, PCG-H (80 < LC50 < 250µg/mL) was categorized as moderately toxic, while PCG-E (LC50 < 80µg/mL) was considered as highly toxic, with its degree of toxicity close to that of the standard drug cyclophosphamide (LC50 = 19.7µg/mL). The results indicate the presence of toxic compounds in the zoanthid obtained from Guadalupe and they suggest caution in the use ofP. caribaeorumas a folk remedy. The variations found in the extracts of the tested Pernambucan populations ofP. caribaeorumcorroborate previous reports that the toxic action of this zoanthid is not inherent to the species, but it is influenced by environmental conditions and associated organisms.

【 授权许可】

Unknown