Lymphoepithelial Thymoma Characterized by Proliferation of Spindle Cells in a Samoyed Dog

Journal of Veterinary Medical Science

Akinori SHIMADA¹  Takehito MORITA¹  Tomomi AKIYAMA¹  Yoshiyuki TAKIMOTO² 

[1] Department of Veterinary Pathology, Tottori University;Takimoto Animal Clinic

关键词: canine;    spindle cell;    thymoma.;   

DOI  :  10.1292/jvms.71.1265

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(12)Cited-By(1)Lymphoepithelial thymoma was diagnosed in a 14-year-old Samoyed dog with clinical symptoms of myasthenia gravis at 6 months of age. At necropsy, dark red-colored mass with many nodular protuberances was found in the anterior mediastinal area. Histologically, the mass consisted of solid proliferation of neoplastic cells with spindle nuclei and cytoplasm and a few lymphocytes, which is separated by an abundant fibrous and adipose tissue. Immunohistochemically, spindle cells were positive for cytokeratin, and infiltrating lymphocytes were positive for CD3. On the basis of these findings, this tumor was diagnosed as lymphoepithelial thymoma, which is morphologically similar to type A thymoma in humans.

【 授权许可】

Unknown