Helicobacter pylori Infection among Children with Phenylketonuria

Japanese Journal of Infectious Diseases

Seçil Arslansoyu²  Ramazan Soylar²  Barış Erdur¹  Yeşim Öztürk² 

[1] Trabzon Numune Training and Research Hospital;Department of Pediatrics, Dokuz Eylul University Faculty of Medicine

关键词: Helicobacter pylori;    phenylketonuria;    phenylalanine;    Turkish children;    phenylalanine restricted diet;   

DOI  :  10.7883/yoken.66.433

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

References(30)This study aimed to determine the frequency of Helicobacter pylori infections in children with phenylketonuria (PKU). Sixty-six children with PKU (35 boys, 31 girls; mean age, 8.2 ± 6.7 years) and 32 outpatient controls (15 boys, 17 girls; mean age, 9.6 ± 4.7 years) were studied. Socioeconomic factors did not differ between the two groups. The frequency of H. pylori infections was higher in patients with PKU (28.1%) than in healthy controls (9.4%). In particular, a higher frequency of infection was detected in patients with PKU with poor metabolic control (51.8%). The frequency of H. pylori infection in patients with PKU with good metabolic control was only 10.2%. There was no difference in the mean total WISC-R score between the poor and good metabolic control groups. A high frequency of H. pylori infection in children with PKU with poor metabolic control could be related to many factors. Advanced and standardized clinical studies on H. pylori infections in children with PKU are required.

【 授权许可】

Unknown