IGF-I and IgG serum concentrations and in mammary secretions in cows treated with rbST prepartum

Revista Brasileira de Zootecnia

Bagaldo, Adriana Regina¹  Lanna, Dante Pazzanese Duarte¹  Machado Neto, Raul¹  Paz, Cláudia Cristina Paro de²  Pauletti, Patricia¹  Kindlein, Liris¹ 

[1] USP, Piracicaba;Instituto de Zootecnia, Ribeirão Preto

关键词: colostrum;    immunoglobulins;    insulin like growth factor-I;    somatotropin   IntroduçãoO colostro é a primeira secreção láctea liberada após o parto e;    em bovinos;    consiste da mistura de secreções da glândula mamária e elementos do soro sangüíneo;    principalmente imunoglobulinas;    que se acumulam durante o período pré-parto;   

DOI  :  10.1590/S1516-35982005000300031

学科分类：兽医学

来源: Universidade Federal de Vicosa

【 摘 要 】

Forty-two Holstein cows, pregnants and multiparous, wereassigned randomly to two groups to determine the possible alterations of IGF-I concentration in colostro and mammary secretions by changes in pre-partum blood serum IGF-I concentration, and also to compare its temporal changes with the serum immunoglobulin G (IgG) in pre-partum period. The treated group (n=21) received 500 mg of recombinant bovine somatotropin (rbST), and the control group (n=21) vitamin E injections. The treatments had been initiated 35 days pre-partum and repeated each 14 days until partum. Weekly it was evaluated body condition scores and was collected blood by mammary venepuncture until partum. Colostrum and mammary secretions were collected daily for seven days pos-partum. Body condition scores and nonesterified fatty acid concentration did not differ between the groups. To the rbST group IGF-I concentration was superior on second and fourth weeks after the treatment had been initiated. However, no treatment differences were found at partum. Concentration of IGF-I was superior in colostrum of cows treated with rbST, but it did not differ in subsequent mammary secretions. IgG serum concentration did not differ between treatments during the experimental period, neither in colostrum and subsequent mammary secretions. IGF-I and IgG serum concentrations showed different responses according to the experimental period, which differed at the range and reflected the main changes that happened at the last month of gestation.

【 授权许可】

CC BY-NC