Malignant Pleural Mesothelioma in a Woodchuck (Marmota monax)

Journal of Veterinary Medical Science

Sang-Koo LEE²  Byeong-Cheol KANG¹  Yong-Soon LEE³ 

[1] Xenotransplantation Research Center, Seoul National University Hospital;Department of Experimental Animal Research, Clinical Research Institute, Seoul National University Hospital;Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University

关键词: mesothelioma;    neoplasia;    woodchuck;   

DOI  :  10.1292/jvms.66.1617

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(10)Cited-By(2)A spontaneous pleural mesothelioma was observed in a 4-year-old female woodchuck (Marmota monax). At necropsy, multifocal, tan to white, firm discrete nodules, 2 to 40mm in diameter, were scattered over the ventral parts of the lungs and their corresponding parts of the diaphragm and the thoracic wall. Histopathologically, the tumor cells were large, cuboidal-shaped and variable size, and were weakly positive with PAS and Alcian blue. Immunohistochemically, neoplastic cells were positive for both vimentin and cytokeratin, indicating mesothelial origin. This report represents, as far as we know, the first reported case of a spontaneous mesothelioma in woodchucks.

【 授权许可】

Unknown