Localized pulmonary histiocytic sarcomas in Pembroke Welsh Corgi

Journal of Veterinary Medical Science

Yuko NAKANO²  Satoshi TAKAGI³  Tetsuya KOBAYASHI²  Yumiko KAGAWA¹  Kazushi ASANO⁴ 

[1] North Lab, 8�?35 Hondori 2-chome Kita, Shiroishi-ku, Sapporo, Hokkaido 003�?0027, Japan;Japan Small Animal Cancer Center, 2�?27�?4, Nakatomi-Minami, Tokorozawa, Saitama 359�?0003, Japan;Veterinary Teaching Hospital, Graduate School of Veterinary Medicine, Hokkaido University, Hokkaido 060�?0818, Japan;Laboratories of Veterinary Surgery, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252�?0880, Japan

关键词: histiocytic sarcoma;    lung;    Pembroke Welsh Corgi;   

DOI  :  10.1292/jvms.15-0284

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(10)Nineteen cases of histiocytic sarcomas in Pembroke Welsh Corgi were examined histopathologically. Focal or multiple masses were detected in the lung or in regional lymph nodes, or in both lung and nodes. All neoplastic lesions had common histological features characterized by the proliferation of pleomorphic histiocytic cells combined with various inflammatory cells. Most of the pleomorphic neoplastic cells were immunopositive for human leukocyte antigen (HLA)-DR and Iba-1. The median survival time for all dogs was 133 days. In the present study, several prognostic factors, such as gender, age, single or multiple lesions, lymph node involvement at the time of diagnosis, surgical resection status and additional chemotherapy, were examined, although none of these factors approached statistical significance. Histiocytic sarcoma must be considered in the differential diagnosis of dogs with pulmonary masses, especially in the canine breed.

【 授权许可】

Unknown