Journal of Chemical Biology | |
Modeling morphological instabilities in lipid membranes with anchored amphiphilic polymers | |
F. Campelo1  | |
[1] Cell and Developmental Biology Programme, Centre for Genomic Regulation (CRG), Doctor Aigüader, 88. 08003 Barcelona, Spain | |
关键词: Lipid bilayer; Morphological instability; Curvature; Bending phase-field models; | |
DOI : 10.1007/s12154-009-0020-z | |
学科分类:分子生物学,细胞生物学和基因 | |
来源: Springer | |
【 摘 要 】
Anchoring molecules, like amphiphilic polymers, are able to dynamically regulate membrane morphology. Such molecules insert their hydrophobic groups into the bilayer, generating a local membrane curvature. In order to minimize the elastic energy penalty, a dynamic shape instability may occur, as in the case of the curvature-driven pearling instability or the polymer-induced tubulation of lipid vesicles. We review recent works on modeling of such instabilities by means of a mesoscopic dynamic model of the phase-field kind, which take into account the bending energy of lipid bilayers.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201911300585955ZK.pdf | 750KB | download |