Effect of Ovary Lipid of Skipjack Tuna on Rat Serum Components after Stress Application

Journal of Veterinary Medical Science

Katumasa OOKAWA²  Kazuo MOCHIZUKI²  Chiaki ITO¹  Yoshikuni SUGIMOTO²  Toru MATUMOTO³  Toshihiro SUZUKI²  Hidehiko YOKOGOSHI⁴  Masayuki HASHIZUME³  Tomoko KITAGAWA³ 

[1] Shizuoka Industrial Creation Organization (Current Fujicco Co., Ltd.);Shizuoka Industrial Research Institute of Shizuoka Prefecture;Maruhachi Muramatsu, Inc.;University of Shizuoka

关键词: corticosterone;    dehydroepiandrosterone;    docosahexaenoic acid;    Ovary lipid;    stress;   

DOI  :  10.1292/jvms.69.49

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(18)Cited-By(5)Lipid extracted from the ovary of skipjack tuna by the method that we developed is rich in phospholipid-type docosahexaenoic acid. The ovary lipid of skipjack tuna (OLS) was studied for its anti-stress activity in male Wistar rats, focusing on stress-related blood components: recovery from stress was examined after application of water immersion restraint stress. As a result, serum corticosterone (CORT) secretion was inhibited and decreased rapidly after stress application in rats given OLS compared with control rats. As CORT acts as a glucocorticoid, non-esterified fatty acid (NEFA) is expected to increase by stress application. However, the concentration tended to be lower in rats given OLS than in control rats. With respect to OLS concentration, OLS increased serum dehydroepiandrosterone, secretion concentration-dependently. In addition, as with the recovery study, it tended to inhibit the increase in NEFA. These results indicate that OLS may have an anti-stress activity against acute stress.

【 授权许可】

Unknown