Comparison of the Effects of Isotonic and Hypertonic Sodium Bicarbonate Solutions on Acidemic Calves Experimentally Induced by Ammonium Chloride Administration

Journal of Veterinary Medical Science

Ryuji ASANO²  Kazuyuki SUZUKI¹  Shigehiro IWABUCHI¹  Izumi ABE¹ 

[1] Central Research Laboratories, Nippon Zenyaku Kogyo Co., Ltd.;Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University

关键词: calf;    metabolic acidosis;    sodium bicarbonate solution;   

DOI  :  10.1292/jvms.65.1369

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(18)Cited-By(5)The objectives of this study were to evaluate and compare the effects of intravenously (IV) administered infusion of isotonic solution (ISB) or hypertonic sodium bicarbonate solution (HSB) on acid-base equilibrium and the plasma osmolarity in acidemic calves experimentally induced by 5 M-NH4Cl, IV infusion (1.0 ml/kg, over 1 hr). The ISB and HSB infusion induced progressive and significant increases in their HCO3- and BE levels that persisted throughout the period of fluid administration. The plasma osmolarity in the ISB groups was significantly decreased. The plasma osmolarity in the HSB group was significantly higher than in the calves in the other groups (p<0.05). ISB solution might be safe and effective for treating and reviving conscious calves from experimentally induced metabolic acidosis.

【 授权许可】

Unknown