Uterine Adenocarcinoma with Prominent Desmoplasia in a Geriatric Miniature Pig

Journal of Veterinary Medical Science

Hossain Md. GOLBAR¹  Jyoji YAMATE¹  Mitsuru KUWAMURA¹  Shu ITO²  Takeshi IZAWA¹ 

[1] Laboratory of Veterinary Pathology, Life and Environmental Sciences, Osaka Prefecture University;Adventure World AWS Co., Ltd.

关键词: desmoplasia;    miniature pig;    uterine adenocarcinoma;   

DOI  :  10.1292/jvms.09-0372

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(16)Cited-By(3)A 10-year-old miniature sow was died, showing inappetence and weight loss. Grossly, neoplastic enlargement of the uterus was found. Histopathologically, the lesions consisted of acinar, ductular and cystic proliferations of mono- and multilayered epithelial cells; these cells reacted immunohistochemically strongly with three different cytokeratin antibodies, and occasionally to vimentin. Myofibroblastic desmoplastic cells, positive to α-smooth muscle actin, were present among neoplastic cells. Metastatic lesions were seen in the lungs and liver. Based on these findings, a diagnosis of uterine adenocarcinoma with marked desmoplasia was made. This case is the second report of uterine adenocarcinoma in the miniature pig.

【 授权许可】

Unknown