Canine Bcl-xL Gene and Its Expression in Tumor Cell Lines

Journal of Veterinary Medical Science

Atsuhiko HASEGAWA¹  Junichi SANO¹  Keisuke OGUMA¹  Rui KANO¹ 

[1] Department of Pathobiology, Nihon University School of Veterinary Medicine

关键词: Bcl-xL;    canine;    cloning;    RT-PCR;   

DOI  :  10.1292/jvms.65.149

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(28)Cited-By(5)The canine Bcl-xL gene was cloned and sequenced. Canine Bcl-xL cDNA clone was 1252 bp in length, and encoded 233 deduced amino acides. The predicted canine Bcl-xL amino acid sequence shared 99.6%, 97.0%, 97.9%, 98.7% and 98.3% homology with that of human, mouse, rat, sheep and pig Bcl-xL, respectively. RT-PCR analysis revealed that canine Bcl-xL mRNA was constitutively expressed in CL-1 (canine lymphoma) and GL-1 (canine B cell leukemia) cell lines.

【 授权许可】

Unknown