Acute copper poisoning in sheep

Ciência Rural

Bassuino, Daniele Mariath¹  Cruz, Claudio Estevão Farias da¹  Driemeier, David¹  Bandinelli, Marcele Bettim¹  Pavarini, Saulo Petinatti¹  Gomes, Danilo Carloto¹  Wouters, Flademir¹  Wurster, Fabiana¹ 

[1] Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brasil

关键词: copper;    acute poisoning;    necrosis hepatic;    sheep;    pathology;   

DOI  :  10.1590/S0103-84782013001000021

学科分类：农业科学（综合）

来源: Universidade Federal de Santa Maria * Centro de Ciencias Rurais

【 摘 要 】

Cases of acute copper intoxication in Santa Ines sheep are described. The disease occurred on a farm in Rio Grande do Sul. Three ewes that had recently lambed and that were fed cattle diet became severely ill and died one week after ingestion of a commercial mineral mix for beef cattle. The sheep showed anorexia, lateral and sternal recumbency, fasciculation and muscle stiffness and death. At necropsy from one of these sheep, the main changes were moderate hepatomegaly, prominent hepatic lobular pattern, and multifocal randomly distributed erosions and ulcerations on the abomasal mucosa. Histological evaluation of the liver showed marked centrilobular hepatocellular necrosis; diffuse hepatocyte swelling predominantly in the periportal area, and a few Kupffer cells contained cytoplasmic pigment granules. The diagnosis was based on the clinical history, necropsy and histopathologic findings, and confirmed by the high copper concentrations detected in the liver, feed, and mineral mix samples.

【 授权许可】

CC BY-NC