Protective role of vitamin C against lindane toxicity on the histo-architecture of the epididymis and vas deferens of male mice ( Mus musculus )

Egyptian Journal of Biology

VK Shrivastava¹  V Gautam¹ 

关键词: Botanicals;    calcitonin;    calcium;    teleost;   

DOI  :  

学科分类：生物科学（综合）

来源: Egyptian-English Society for Biological Sciences

【 摘 要 】

We studied the protective effects of vitamin C against the toxic effects of lindane on the epididymis and vas deferens of male mice. There were four treatments: controls (untreated), lindane (20 mg/kg), lindane plus vitamin C (10 mg/kg) and vitamin C only. Lindane induced histopathological alterations in the epididymis and vas deferens characterized by a reduced epithelium with degenerative changes in the muscular layers and connective tissues, and a lack of spermatozoa in the lumen of both epididymis and vas deferens. These changes were restored towards normalcy by vitamin C. These results suggest that vitamin C has some protective role against lindane toxicity in epididymis and vas deferens of male mice.

【 授权许可】

Unknown