Radiomorphometric Quantitative Analysis of Vasculature Utilizing Micro–Computed Tomography and Vessel Perfusion in the Murine Mandible

Craniomaxillofacial Trauma and Reconstruction

Steven R. Buchman¹  Aaron S. Farberg¹  Xi Lin Jing¹  Laura A. Monson¹  Alexis Donneys¹  Catherine N. Tchanque-Fossuo¹ 

[1] Department of Plastic Surgery, University of Michigan, Ann Arbor, Michigan

关键词: vessel perfusion;    micro-CT;    murine mandible;    vascularity;   

DOI  :  10.1055/s-0032-1329540

学科分类：口腔科学

来源: Thieme Medical Publishers, Inc.

【 摘 要 】

Purpose Biomechanical, densitometric, and histological analyses have been the mainstay for reproducible outcome measures for investigation of new bone formation and osseous healing. Here we report the addition of radiomorphometric vascular analysis as a quantitative measure of vascularity in the murine mandible. To our knowledge this is the first description of using micro–computed tomography (micro-CT) to evaluate the temporal and spatial pattern of angiogenesis in the craniofacial skeleton.

【 授权许可】

Unknown