Insulinoma in a Patient With Non-Insulin-Dependent Diabetes Mellitus

Endocrine Journal

KUNIO YOSHIZAWA¹  YOSHIHIKO SATO³  AKIHIRO SAKURAI³  GENGO KANEKO²  KIYOSHI HASHIZUME³  MASAFUMI KATAKURA¹  TORU AIZAWA³ 

[1] Asama General Hospital;Department of Surgery II, Shinshu University School of Medicine;Department of Geriatrics, Endocrinology and Metabolism, Shinshu University School of Medicine

关键词: Insulinoma;    Diabetes;    Pancreas tumor;   

DOI  :  10.1507/endocrj.44.473

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(22)Cited-By(14)Insulinoma in a patient with pre-existing diabetes is exceedingly rare. Only a small number of well-documented cases have been reported in the world during the last 40years. We describe a case with non-insulin-dependent diabetes mellitus who after seven years of sulfonylurea treatment experienced recurrent episodes of hypoglycemia. Endogenous hyperinsulinism was found and radiographical examination and transhepatic venous sampling confirmed an insulin secreting pancreatic tumor. After surgical excision of the tumor, patient was relieved from hypoglycemic attacks but required to initiate insulin injection for the treatment of hyperglycemia.

【 授权许可】

Unknown