Journal of Veterinary Medical Science | |
Immunological Responses to Polyvalent Canine Vaccines in Dogs | |
Tadashi MIYAMOTO1  Seiji WATANABE1  Makoto YOSHITAKE1  Sanenori NAKAMA1  Satoshi UNE1  Yasuho TAURA1  | |
关键词: canine; immunological response; vaccination; | |
DOI : 10.1292/jvms.57.347 | |
学科分类:兽医学 | |
来源: Japanese Society of Veterinary Science | |
【 摘 要 】
References(13)Cited-By(5)The immunological responses to commercially available polyvalent vaccines in dogs were examined. There was a tendency in decreased lymphocyte counts on day 7 in the puppy and adult dogs. There was a significant increase in the blastogenesis of lymphocytes on day 7 and 21 in puppies, whereas no significant changes were seen in the adult dogs. Delayed type hypersensitivity (DTH) responses to phytohemagglutinin (PHA) and canine parvo-virus (CPV) vaccine monitored 0, 3, 8 weeks after vaccination produced strong reactions, in particular those to CPV vaccine rose significantly after vaccination and maintained the higher responses for at least 2 months. Therefore, it is considered that vaccination is immunomodulative rather than immunosuppressive and that DTH responses to PHA and CPV vaccine are helpful to monitor non-specific and specific immune functions in vivo.
【 授权许可】
Unknown
【 预 览 】
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RO201911300406385ZK.pdf | 524KB | download |