Seroprevalence, Seroconversion, and Risk Factors for Toxoplasmosis among Pregnant Women in Taipei, Taiwan

Japanese Journal of Infectious Diseases

Chia-Kwung Fan²  Yin-Chin Wang²  Akiko Tsubouchi¹  Giueng-Chueng Wang³  Ching-Sheng Hung³  Toshio Naito⁴  Hui-Wen Weng³  Hung-Wen Su⁵  Yu-Luen Lee⁶ 

[1] Research Support Center, School of Medicine, Juntendo University;Department of Molecular Parasitology and Tropical Diseases, College of Public Health and Nutrition, Taipei Medical University;Department of Laboratory Medicine, Wan Fang Hospital;Department of General Medicine, Juntendo University;Department of Obstetrics and Gynecology, Wan Fang Hospital;Department of Microbiology and Immunology, College of Public Health and Nutrition, Taipei Medical University

关键词: Toxoplasma gondii;    pregnant women;    seroprevalence;    risk factors;    Taipei;   

DOI  :  10.7883/yoken.JJID.2014.263

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

References(33)Cited-By(1)Herein, we determined the seroprevalence, seroconversion, and risk factors associated with Toxoplasma gondii (T. gondii) infection among pregnant women in Taipei, Taiwan. Pregnant women attending antenatal consultation in a Taipei medical center were invited, and 104 women completed a self-administered structured questionnaire. Venous blood samples were collected during the first and third trimester after consent was obtained. Serum IgG and IgM antibodies (Abs) as well as IgG avidity were analyzed using an enzyme-linked fluorescent assay. Of the samples collected in the first trimester, seven were seropositive for IgG Abs and one was seropositive for IgG + IgM Abs with a borderline avidity index, resulting in an overall seroprevalence of 7.7%. No statistically significant association was found between toxoplasmosis and age, pregnancy history, or any risk factors. Seroconversion was not detected from paired sera between the first and third trimesters. Pregnant women with senior high school education level or those who claimed to knowing Toxoplasma exhibited a significantly higher seroprevalence than those with bachelor degree (P = 0.05) or those who claimed not to have this knowledge (P = 0.05). Therefore, failure to understand the importance of T. gondii infection and the prevention measures resulted in the development of toxoplasmosis among these women.

【 授权许可】

Unknown