Effect of an E2 vaccine candidate of classical swine fever on bioproductive indicators at a pig farm

Revista de Salud Animal

Domínguez, Patricia²  Chong, Daine¹  Rodríguez, María Pilar¹  Fonseca, Osvaldo²  Frías, María Teresa²  Ferrer, Edyniesky²  Percedo, María Irian²  Suárez, Marisela¹  Castell, Sara² 

[1] Centro de Ingeniería Genética y Biotecnología (CIGB), Cuba;Centro Nacional de Sanidad Agropecuaria (CENSA), San José de Las Lajas, Cuba

关键词: pigs;    Classical Swine Fever;    vaccine;    E2 subunit protein;    bioproductive indicators;   

DOI  :  

学科分类：兽医学

来源: Centro Nacional de Sanidad Agropecuaria

【 摘 要 】

Classical swine fever (CSF) belongs to the group of diseases classified as notifiable to the World Organization for Animal Health (OIE). Prophylactic and systematic vaccination with modified live virus has been the main strategy for controlling CSF in large endemic areas, although, to meet their limitations, the so-called «marker vaccines» have been developed. In Cuba, a new vaccine candidate against CSF virus has been developed based on the E2 glycoprotein of its viral envelope (CVE2). After passing successfully through a series of laboratory tests, its evaluation under field conditions was required; as part of the various experiments carried out, it was decided to evaluate the behavior of the bioproductive indicators at a farm before and after the application of CVE2. The studies were conducted at a pig farm with a history of CSF endemism for several years where the animals were regularly vaccinated with the lapinized Chinese strain vaccine (LABIOFAM S.A.) as part of the control of the disease and the CVE2 began to be applied. After the CVE2 application, improvement of the bioproductive indicators was observed in the population studied.

【 授权许可】

CC BY-NC