Effect of Intravenous Infusion of Isotonic Sodium Bicarbonate Solution on Acidemic Calves with Diarrhea

Journal of Veterinary Medical Science

Ryuji ASANO²  Kazuyuki SUZUKI²  Kimi ASANO²  Shigehiro IWABUCHI³  Tosihide KATO⁴  Gensei TSUNODA¹ 

[1] Fukushima Prefectural Federation of Agricultural Mutual Aid Associations;Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University;Central Research Laboratories, Nippon Zenyaku Kogyo Co., Ltd;Yamagata Prefectural Federation of Agricultural Mutual Aid Associations

关键词: acid-base equilibrium;    calf;    sodium bicarbonate;   

DOI  :  10.1292/jvms.64.1173

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(18)Cited-By(5)The effect of 1.35% isotonic sodium bicarbonate solution (ISB) administered intravenously on acid-base equilibrium was examined in 18 acidemic Japanese black beef calves with spontaneous diarrhea. The infusion volumes of ISB were decided based on the first half volumes of base needed. In 72.2% (13/18) of calves, improvement of acidemia was detected. There was good correlation (r=0.693, p<0.01) between infused volume of ISB and changes in base excess (y=1.097x + 4.762). Infusion volumes of ISB were 7.5, 10.2, 12.9 and 15.7 ml/kg, respectively, enough to correcting the first half of 5, 10, 15 and 20 mEq/l of base deficit in acidemic calves. Our finding suggested that ISB could be used to correct metabolic acidosis without altering electrolyte concentrations in calves.

【 授权许可】

Unknown