Rumen Bacteria are Involved in the Onset of Onion-induced Hemolytic Anemia in Sheep

Journal of Veterinary Medical Science

Motoshi Tajima²  Yoshimitsu Maede²  Hatem Mohamed Selim¹  Osamu Yamato² 

[1] Department of Internal Medicine, Faculty of Veterinary Medicine, Zagazig University, Egypt;Laboratory of Internal Medicine, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan

关键词: Heinz body;    hemolytic anemia;    onion;    rumen microorganism;    ruminant;   

DOI  :  10.1292/jvms.61.369

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(24)Cited-By(1)The mechanism of onion-induced hemolytic anemia in ruminants was investigated. The ether-extract obtained from the mixture of rumen fluid and onion juice incubated at 38.5°C for 9 hr induced oxidative damage in sheep erythrocytes in vitro, indicating the production of certain oxidants in the mixture. The increase of the oxidative effect in the mixture was inhibited completely by the removal of rumen microorganisms and partly by treatment with antibiotics and by oxygen gas. The sheep fed onions (50 g/kg body weight/day) for 15 days developed more severe Heinz body hemolytic anemia than did the sheep fed the equivalent amount of onions with 5 g/day ampicillin sodium salt. The results indicated that certain rumen bacteria appear to be involved in the onset of onion-induced hemolytic anemia in sheep.

【 授权许可】

Unknown