Small clonal B-cell population in the bone marrow as a possible tool in the diagnosis of occult primary parotid lymphoma

Colombia Médica

Guido R. González-Fontal¹  Mónica Duarte²  Andrés F. Henao-Martínez³  Martha Romero⁴  Carlos Saavedra⁴ 

[1] Division of Hemato-Oncology. Clínica Rey David, Cali, Colombia;Hematology. Fundación Santa Fe de Bogotá, Bogotá, Colombia;University of Colorado Denver;Department of Pathology. Fundación Santa Fe de Bogotá, Bogotá, Colombia

关键词: B-lymphocytes;    bone marrow;    diagnosis;    lymphoma;    parotid gland;   

DOI  :  

学科分类：医学（综合）

来源: Universidad del Valle * Facultad de Salud / Universidad del Valle, Faculty of Health

【 摘 要 】

Case Description: An82-years old Hispanic woman with a past medical history significant forpulmonary thromboembolism on oral anticoagulation, rheumatoidarthritis, and hypertension developed a new onset thrombocytopenia. Clinical Findings: Smallclonal B-cells populations (SCBP) also known as monoclonal B-celllymphocytosis was found as part of the workup for an idiopathicthrombocytopenia and lead ultimately to the diagnosis of parotid primaryfollicular lymphoma coexisting with Warthin tumor involving the bonemarrow in a small extent and oncocytic papilloma located in themaxillary sinus. Treatment and Outcome: Patient was treated with Rituximab monotherapy with improvement on her platelet count. Clinical relevance: Althoughit is unclear the role of this clonal cells, they may work as apossible diagnostic tool for occult lymphomas. Further prospectivestudies are needed to confirm this possible association.

【 授权许可】

Unknown