Ginger Supplementation Enhances Working Memory of the Post-Menopause Women | Science Publications

American Journal of Applied Sciences

Chuleratana Bunchonglikitkul¹  Nawanant Piyavhatkul¹  Naritsara Saenghong¹  Supaporn Muchimapura¹  Terdthai Tong-Un¹  Tanwarat Kajsongkram¹  Jintanaporn Wattanathorn¹ 

关键词: Ginger rhizome;    Zingiber officinale;    attention impairment;    working memory;    post-menopausal women;    computerized battery;    ginger extract;    intellectual function;   

DOI  :  10.3844/ajassp.2011.1241.1248

学科分类：自然科学（综合）

来源: Science Publications

【 摘 要 】

Problem statement: Cognitive impairment is one important problem in post-menopausal women. Although hormone therapy can improve this condition, it also produces adverse effect. Recent findings showed that this condition could be mitigated by the herb. Ginger or Zingiber officinale Roscoe, a plant in a family of Zingiberaceae, was previously demonstrated the neuroprotection and cognitive enhancing effects. Therefore, this study was set up to determine whether ginger rhizome extract could improve attention and working memory of the post-menopausal women. Approach: Sixty healthy post-menopausal women were randomly assigned to receive either placebo or standardized plant extract at doses of 400 and 800 mg once daily for 3 months. After the assessment of biographic information, they were evaluated the working memory and cognitive function using computerized battery test and the auditory oddball paradigm of event related potential before and after 3-month of intervention. Results: The ginger treated group decreased N100 and P300 latencies but increased N100 and P300 amplitudes in accompany with the enhanced working memory including the power of attention, continuity of attention, speed and quality of memory. Conclusion: Our results suggested that ginger is the potential cognitive enhancer for post-menopausal women. However, further researches are still required.

【 授权许可】

Unknown