Hypoglycemic activity of Chamaedorea tepejilote Liebm. (pacaya)

Revista Cubana de Plantas Medicinales

Solórzano Carranza, Erwin R²  Riquett Robles, Davinson J¹ 

[1] Universidad del Atlántico, Colombia;Centro de Apoyo a la Investigación de Productos Naturales, Guatemala

关键词: Chamaedorea tepejilote;    pacaya;    hypoglycemic;    bioassay;   

DOI  :  

学科分类：药理学

来源: Editorial Ciencias Medicas

【 摘 要 】

Introduction: Chamaedorea tepejilote Liebm. is native from Mexico, Central America, Panama and the Pacific Coast of Colombia. This palm called pacaya in Central America is a traditional food of strong roots in Guatemala, El Salvador and Honduras. The only use of the inflorescences of the pacaya that is so far known is traditional food; however, some people attribute some medicinal qualities to them. Objectives: to obtain and to evaluate the hypoglycemic activity of dried aqueous extract of male inflorescences of Chamaedorea tepejilote Liebm. Methods: the effect of Chamaedorea tepejilote (Pacaya) on the glycemia of normal mice was studied. The hypoglycemic effect of intraperitoneal dose of the extract (100, 200 y 300 mg/kg) in blood samples taken from the tail vein at 2, 6 and 24 h was measured after administration. Results: the administration of 300 mg/kg of Chamaedorea tepejilote extract to normal mice reduced blood glucose levels by 29.77 %. Conclusions: the hypoglycemic effect of this plant extract that is used in traditional medicine for diabetes treatment was confirmed.

【 授权许可】

CC BY-NC