Hypoglycemic and hypocholesterolemic effects of aqueous and methanolic extracts of Lentinus lepideus, Calvatia cyathiformis and Ganoderma applanatum, from Northeastern Mexico, in Wistar rats

Dynamic Chiropractic

Fortunato Garza-Ocantilde¹  Eduardo Javier Tamez de la O²  eda⁴  Maria Teresa Zanatta-Calderon⁴  Christian Tadeo Badillo-Castantilde⁵  as⁶  Lourdes Garza-Ocantilde⁶  Ruben Lujan-Rangel⁷  Xochitl Sofia Ramirez Gomez⁷ 

[1] Forestry Faculty, Universidad AutóPharmacology and Toxicology Department, School of Medicine, Universidad AutóSchool of Medicine, Universidad de Guanajuato, Mén, Mén, Monterrey, Nuevo Leónoma de Nuevo Leóxico.

关键词: Basidiomycetes;    hypoglycemic;    hypocholesterolemic;    glibenclamide.;   

DOI  :  10.5897/JMPR12.875

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

The hypoglycemic and hypocholesterolemic activity of three fungi basidiomycetes from Northeastern Mexico were investigated in this study. Aqueous and methanolic extracts fromLentinus lepideus,Calvatia cyathiformisandGanoderma applanatumwere orally administered to alloxan-induced diabetic rats. Blood glucose and cholesterol was determined using an Accutrend Glucometer (Roche, Germany) at 0, 3 and 6 h after treatment administration. The rats that received the methanolic extract ofL. lepideushad significantly lower glycemic levels at 3 (30%) and 6 h (35%). In contrast, the methanolic extracts ofC. cyathiformisandG. applanatumhad no significant differences when compared with the control group. No statistical difference in cholesterol levels was observed in the experimental groups when compared with the control group with any of the administered extracts.

【 授权许可】

Unknown