Local application of platelet lysate on posflebitic ulcers

Revista Cubana de Hematología, Inmunología y Hemoterapia

Fernández-Delgado, Norma¹  Ford Revol, Daniel²  Saavedra-Martínez, Niurka²  Semino Baffil, Bernardo²  Sanabria-Negrín, José G³  Pérez-Mesa, Dayma S²  Rodríguez-Orta, Celia de los A²  González-Cordero, Francisco²  Hernández-Ramírez, Porfirio¹  Santos-Saavedra, Yudith²  Arteaga-Báez, Juan M²  Gámez-Pérez, Anadely²  Borrego-Rodríguez, Beatriz²  González-Portales, Yaneisy² 

[1] Instituto de Hematología e Inmunología, La Habana, Cuba;Hospital General Docente Comandante Pinares, Artemisa, Cuba;Universidad de Ciencias Médicas de Pinar del Río, Pinar del Río, Cuba

关键词: posflebitic ulcer;    platelet lysate;    lower limbs;    topical;    outpatient care;   

DOI  :  

学科分类：生理学与病理学

来源: SciELO

【 摘 要 】

Treatment of post-thrombotic ulcers or postflebitic is a challenge to medicine because of its chronicity and frequent recurrences that determine multiple local and systemic disorders with poor quality of life for patients. This study included 80 patients with lower limb posflebitic ulcers, who were grouped into 2 groups: 40 treated with preserved allogeneic platelet lysates and 40 were treated conventionally. The latter was the control group. It was considered good result when the patient had a partial or complete response after 30 days of treatment or before. Good response was found in 95% of patients treated with lysate (sum of total and partial values) versus 75% in the control group (p> 0.001). The use of platelet lysate was a simple and effective procedure in the treatment of lower limb posflebitic ulcers. This treatment can be recommended, since patients can stay at home, thus eliminating the hospital costs incurred in this type of treatment.

【 授权许可】

Unknown