Prevalence of precursory lesions of cancer in HIV positive, individuals assisted at Fundação de Medicina Tropical do Amazonas, initial experience in Manaus

Revista Brasileira de Coloproctologia

Atala, Larissa de Souza²  Rocha, Renata Pina²  Guimarães, Adriana Gonçalves Daumas Pinheiro²  Talhari, Sinésio¹  Araújo, José de Ribamar¹  Ferreira, Luiz Carlos de Lima²  Gimenez, Felicidad Santos²  Avi, Sabrina Veloso²  Silva, Ivan Tramujas da Costa e² 

[1] Fundação de Medicina Tropical do Amazonas;Universidade Federal do Amazonas

关键词: Prevalence;    anal cancer;    HIV;   

DOI  :  10.1590/S0101-98802008000100010

学科分类：心脏病和心血管学

来源: Sociedade Brasileira de Coloproctologia

【 摘 要 】

The anal cancer accounts approximately for 2% of the cases of colorectal cancer. In the last few years it has been observed an increase in the incidence of this disease in HIV-positive individuals. The objective of this study is to evaluate the prevalence of anal squamous intraepithelial lesions (ASIL) in HIV-positive patients which are resident in Manaus. Forty-five HIV+ patients were included in the study, from which it was collected anal mucosal tissue for biopsy under anoscopic control using widened image for histopathological exam. According to this exam, it was found the following results: 15(35,7%) low grade lesions, 3(7,1%) high grade lesions and 24 (57,2%) negative for ASIL. Therefore, there was a high prevalence of ASIL, 42,8%. We concluded that the prevalence of ASIL among HIV-positive patients, in the studied sample, is very important, justifying the implementation of a program of precocious monitoring and detection of these lesions, as the HIV+ patients represent an important risk group for the developing of anal cancer.

【 授权许可】

CC BY-NC