Histopathological changes in liver and gill epithelium of Nile tilapia, Oreochromis niloticus, exposed to waterborne copper

Pesquisa Veterinária Brasileira

Matos, Pedro¹  Carrola, João¹  Monteiro, Sandra M.¹  Fontaínhas-Fernandes, António¹  Garcia-Santos, Sofia¹  Figueiredo-Fernandes, António¹  Ferreira-Cardoso, Jorge V.¹ 

[1] Universidade de Trás-os-Montes e Alto Douro, Portugal

关键词: Copper;    gill;    liver;    histopathological changes;    Oreochromis niloticus;    Teleostei.;   

DOI  :  10.1590/S0100-736X2007000300004

来源: Colegio Brasileiro de Patologia Animal-CBPA

【 摘 要 】

Nile tilapia, Oreochromis niloticus, of both sexes were reared in freshwater and exposed to 0.5, 1.0 and 2.5mg L-1 of waterborne copper for a period of 21 days. Liver and gill samples were collected after 21 days of exposure to copper and lesions were analyzed by light microscopy. The main histopathological changes observed in gills exposed to the highest concentration were edema, lifting of lamellar epithelia and an intense vasodilatation of the lamellar vascular axis. Although less frequent, lamellar fusion caused by the filamentar epithelium proliferation and some lamellar aneurisms were also found. The liver of control group exhibited a quite normal architecture, while the fish exposed to copper showed vacuolation and necrosis. These hepatic alterations were more evident in fish exposed to 1.0 and 2.5mg L-1 copper concentrations. The number of hepatocytes nucleus per mm2 of hepatic tissue decreased with the increase of copper concentration. In contrast, the hepatic somatic index was high in fish exposed at 2.5mg L-1 of copper. In short, this work advance new knowledge as influence of copper in the gill and liver histology of O. niloticus and demonstrated that their effects could be observed at different concentrations. Index

【 授权许可】

CC BY-NC